I finally managed to solve the problem with the following solution.
I flashed the Bios with the 2.5 Supplemental CD and disabled AMD PowerNow! and the PS/2 Port in the Bios settings.
I have a W1100z with an AMD Opteron 150 and it seems, that this CPU does not support AMD PowerNow! As the machine does not have an PS/2 Port I disabled it in the BIOS.
After that, the problems with the mouse shutter were gone. Maybe it is helpful for someone else.